Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409336 | 0.76 | HPGD (0.49) | KCNH2CYP19A1 | |
| SCHEMBL4414660 | 0.74 | HPGD (0.50) | CYP19A1 | |
| SCHEMBL7622071 | 0.72 | MEN1 (0.47) | — | |
| SCHEMBL6940091 | 0.72 | MEN1 (0.47) | — | |
| SCHEMBL6943100 | 0.71 | — | — | |
| SCHEMBL4412019 | 0.69 | HPGD (0.51) | CYP19A1 | |
| SCHEMBL9381324 | 0.69 | KMT2A (0.47) | — | |
| SCHEMBL4403680 | 0.68 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL4407677 | 0.67 | FAAH (0.43) | KCNH2CYP19A1 | |
| SCHEMBL4409333 | 0.66 | MIF (0.33) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |