Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 12/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 11/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946034 | 0.85 | PTPN1 (0.53) | PTPN1FEN1ERCC5HAO1 | |
| SCHEMBL6951641 | 0.81 | FEN1 (0.54) | PTPN1LMNASMN1; SMN2FEN1ERCC5 | |
| Dimethylamine SCHEMBL6943573 | 0.81 | PTPN1 (0.69) | PTPN1FEN1ERCC5HAO1 | |
| SCHEMBL6947650 | 0.80 | PTPN1 (0.72) | PTPN1FEN1ERCC5HAO1 | |
| SCHEMBL6943298 | 0.77 | PTPN1 (0.46) | PTPN1KDM4EFEN1ERCC5HAO1 | |
| SCHEMBL6949821 | 0.72 | PTPN1 (0.64) | PTPN1LMNAFEN1ERCC5HAO1 | |
| SCHEMBL6946193 | 0.72 | PTPN1 (0.67) | PTPN1SMN1; SMN2FEN1ERCC5HAO1 | |
| SCHEMBL6947604 | 0.71 | ERCC5 (0.61) | PTPN1LMNAFEN1ERCC5HAO1 | |
| SCHEMBL6947985 | 0.70 | PTPN1 (0.64) | PTPN1FEN1ERCC5HAO1 | |
| SCHEMBL6946220 | 0.70 | PTPN1 (0.71) | PTPN1FEN1ERCC5HAO1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082121-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2003-02-05 | — | — | EP | claimed |
| US-6380249-B1 | HIV integrase inhibitors | MERCK & CO., INC. | 2002-04-30 | — | — | US | claimed |
| EP-1082121-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2001-03-14 | — | — | EP | claimed |
| WO-1999062520-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 1999-12-09 | — | — | WO | claimed |
| EP-1082121-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2003-02-05 | — | — | EP | disclosed |
| US-6380249-B1 | HIV integrase inhibitors | MERCK & CO., INC. | 2002-04-30 | — | — | US | disclosed |
| EP-1082121-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999062520-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 1999-12-09 | — | — | WO | disclosed |