Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 4/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.65 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.65 |
| ▸ | SHBG | P04278 | 5/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805788 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL6940266 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL20058396 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL6940263 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL17697306 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL19270194 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL17361278 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL24086240 | 0.86 | SHBG (0.52) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL6839452 | 0.84 | CYP19A1 (0.64) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL6839455 | 0.84 | CYP19A1 (0.64) | AKR1B10AKR1B1CYP19A1OR51E2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801557-B1 | LIPOSOME FORMULATIONS OF 5BETA STEROIDS | SUPERGEN INC (US) | 2003-07-02 | — | — | EP | disclosed |
| US-6436435-B1 | Liposome formulation of 5 β steroids | SUPER GEN, INC. | 2002-08-20 | — | — | US | disclosed |
| US-5824668-A | Formulation for administration of steroid compounds | SUPERGEN, INC. (US) | 1998-10-20 | — | — | US | disclosed |