Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 11/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5464216 | 0.86 | SIGMAR1 (0.37) | SIGMAR1GPR88MEN1KMT2ACHRNA7 | |
| SCHEMBL5464210 | 0.86 | SIGMAR1 (0.37) | SIGMAR1GPR88MEN1KMT2ACHRNA7 | |
| SCHEMBL7206322 | 0.63 | CA1 (0.36) | — | |
| SCHEMBL7211026 | 0.63 | CHRM2 (0.38) | SIGMAR1MEN1KMT2A | |
| SCHEMBL7207511 | 0.63 | STS (0.48) | MEN1KMT2A | |
| SCHEMBL6507306 | 0.62 | HDAC4 (0.53) | SIGMAR1MEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL7211822 | 0.62 | STS (0.40) | — | |
| SCHEMBL7211202 | 0.62 | CA12 (0.38) | — | |
| SCHEMBL7207611 | 0.61 | CA1 (0.37) | MEN1KMT2A | |
| SCHEMBL7211852 | 0.60 | HRH3 (0.42) | SIGMAR1GPR88ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |