Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451062 | 0.78 | HDAC4 (0.59) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 | |
| SCHEMBL13975670 | 0.78 | HDAC4 (0.59) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 | |
| SCHEMBL29172119 | 0.77 | HDAC4 (0.58) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 | |
| SCHEMBL29172117 | 0.77 | HDAC4 (0.58) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 | |
| SCHEMBL2034678 | 0.75 | FFAR1 (0.70) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 | |
| SCHEMBL5217474 | 0.75 | FFAR1 (0.70) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 | |
| SCHEMBL8295172 | 0.75 | FFAR1 (0.70) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 | |
| SCHEMBL323823 | 0.75 | FFAR1 (0.70) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 | |
| SCHEMBL4126470 | 0.75 | FFAR1 (0.70) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 | |
| SCHEMBL323824 | 0.75 | FFAR1 (0.70) | HDAC4ALDH1A1DEGS1FFAR1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037810-A2 | CYCLOPROPYL METHANONE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2005-04-28 | — | — | WO | claimed |
| WO-2005018541-A2 | COX-2 INHIBITOR AND SEROTONIN MODULATOR FOR TREATING CNS DAMAGE | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |