Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447142 | 0.98 | L3MBTL1 (0.43) | L3MBTL1HRH3KMT2ACYP1A2CHRM2 | |
| SCHEMBL1366353 | 0.92 | PIK3CD (0.47) | KMT2ACYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL4401513 | 0.86 | ADRA1B (0.46) | KMT2ACYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL1446471 | 0.86 | L3MBTL1 (0.46) | L3MBTL1HRH3KMT2ACYP1A2CHRM2 | |
| SCHEMBL4611720 | 0.81 | L3MBTL1 (0.46) | L3MBTL1HRH3KMT2ACYP1A2CHRM2 | |
| SCHEMBL10427076 | 0.81 | L3MBTL1 (0.46) | L3MBTL1HRH3KMT2ACYP1A2CHRM2 | |
| SCHEMBL9156890 | 0.81 | L3MBTL1 (0.46) | L3MBTL1HRH3KMT2ACYP1A2CHRM2 | |
| SCHEMBL8538164 | 0.81 | KMT2A (0.46) | L3MBTL1HRH3KMT2ACYP1A2CHRM2 | |
| SCHEMBL10481709 | 0.81 | L3MBTL1 (0.46) | L3MBTL1HRH3KMT2ACYP1A2CHRM2 | |
| SCHEMBL3512713 | 0.81 | L3MBTL1 (0.46) | L3MBTL1HRH3KMT2ACYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998451-B1 | SUBSTITUTED 3,3-DIAMINO-2-PROPENENITRILES, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 2003-04-16 | — | — | EP | claimed |