Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6944173 | 0.99 | REN (0.56) | RENSIGMAR1CYP3A4TDP1F10 | |
| SCHEMBL6943202 | 0.91 | REN (0.55) | REN | |
| Hydrochloric Acid SCHEMBL6942968 | 0.90 | REN (0.56) | REN | |
| Hydrochloric Acid SCHEMBL6947328 | 0.87 | REN (0.57) | RENTDP1 | |
| SCHEMBL6944413 | 0.84 | REN (0.48) | REN | |
| Hydrochloric Acid SCHEMBL6945622 | 0.84 | REN (0.66) | REN | |
| Hydrochloric Acid SCHEMBL6947816 | 0.84 | REN (0.49) | REN | |
| SCHEMBL6944430 | 0.83 | REN (0.51) | REN | |
| SCHEMBL6947152 | 0.83 | REN (0.51) | REN | |
| SCHEMBL6947040 | 0.83 | REN (0.51) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | claimed |
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |