Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6942968 | 0.99 | REN (0.56) | RENCYP2D6CYP2C9KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6947328 | 0.96 | REN (0.57) | RENCYP2D6CYP2C9KDM4EALDH1A1 | |
| SCHEMBL6944413 | 0.94 | REN (0.48) | RENCYP2D6CYP2C9KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6947816 | 0.93 | REN (0.49) | RENCYP2D6CYP2C9KDM4EALDH1A1 | |
| SCHEMBL6940757 | 0.91 | REN (0.56) | RENCYP2D6CYP2C9KDM4EALDH1A1 | |
| SCHEMBL6944136 | 0.91 | REN (0.55) | REN | |
| Hydrochloric Acid SCHEMBL6944173 | 0.90 | REN (0.56) | REN | |
| SCHEMBL6940726 | 0.89 | REN (0.52) | RENKDM4EALDH1A1GLAHPGD | |
| Hydrochloric Acid SCHEMBL6938981 | 0.88 | REN (0.53) | RENKDM4EALDH1A1GLAHPGD | |
| SCHEMBL6943317 | 0.88 | REN (0.56) | RENCYP2D6CYP2C9KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |