Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 15/20 | 1.00 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951677 | 0.95 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6949942 | 0.95 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6949936 | 0.95 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6948683 | 0.83 | UTS2R (0.80) | UTS2R | |
| SCHEMBL6944246 | 0.83 | UTS2R (0.80) | UTS2R | |
| SCHEMBL6950626 | 0.81 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6948302 | 0.81 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6946573 | 0.81 | UTS2R (1.00) | UTS2R | |
| SCHEMBL2072537 | 0.79 | UTS2R (0.65) | UTS2RSLC6A5DRD4 | |
| SCHEMBL2214839 | 0.79 | UTS2R (0.65) | UTS2RMCHR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244452-B1 | CARBOXAMIDE DERIVATES OF PYRROLIDINE AND PIPERIDINE AS UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-09-17 | — | — | EP | claimed |
| US-6544992-B1 | Carbonylamino pyrrolidine and piperidine derivatives | SMITHKLINE BEECHAM CORPORATION | 2003-04-08 | — | — | US | claimed |
| EP-1244452-A4 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-01-15 | — | — | EP | claimed |
| EP-1244452-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001045711-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-28 | — | — | WO | claimed |
| EP-1244452-B1 | CARBOXAMIDE DERIVATES OF PYRROLIDINE AND PIPERIDINE AS UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-09-17 | — | — | EP | disclosed |
| EP-1244452-A4 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-01-15 | — | — | EP | disclosed |
| EP-1244452-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001045711-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-28 | — | — | WO | disclosed |