Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944246 | 1.00 | UTS2R (0.80) | UTS2R | |
| SCHEMBL6951677 | 0.88 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6949936 | 0.88 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6949942 | 0.88 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6949854 | 0.85 | UTS2R (0.81) | UTS2R | |
| SCHEMBL6949845 | 0.85 | UTS2R (0.81) | UTS2R | |
| SCHEMBL6944245 | 0.83 | UTS2R (1.00) | UTS2R | |
| SCHEMBL6953061 | 0.82 | UTS2R (0.62) | UTS2R | |
| SCHEMBL6596912 | 0.79 | UTS2R (0.59) | UTS2R | |
| SCHEMBL6596908 | 0.77 | UTS2R (0.49) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244452-B1 | CARBOXAMIDE DERIVATES OF PYRROLIDINE AND PIPERIDINE AS UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-09-17 | — | — | EP | claimed |
| US-6544992-B1 | Carbonylamino pyrrolidine and piperidine derivatives | SMITHKLINE BEECHAM CORPORATION | 2003-04-08 | — | — | US | claimed |
| EP-1244452-B1 | CARBOXAMIDE DERIVATES OF PYRROLIDINE AND PIPERIDINE AS UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-09-17 | — | — | EP | disclosed |
| US-6544992-B1 | Carbonylamino pyrrolidine and piperidine derivatives | SMITHKLINE BEECHAM CORPORATION | 2003-04-08 | — | — | US | disclosed |