Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949760 | 0.73 | ADORA2A (0.41) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7076733 | 0.69 | ADORA2A (0.59) | ADORA2AADORA1PIK3R1PIK3CA | |
| SCHEMBL6939895 | 0.65 | ADORA2A (0.75) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL3267809 | 0.63 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL23436456 | 0.59 | XDH (0.49) | ADORA2A | |
| SCHEMBL3269891 | 0.58 | ADORA2A (0.58) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL3270277 | 0.58 | ADORA2A (0.76) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL3267606 | 0.58 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL3269113 | 0.58 | ADORA2A (0.77) | ADORA2AADORA1 | |
| SCHEMBL3310025 | 0.58 | XDH (0.76) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349857-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2003-10-08 | — | — | EP | claimed |
| WO-2002055521-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2002-07-18 | — | — | WO | claimed |