SCHEMBL6944584

SCHEMBL6944584

C=C(c1c(C)n(CC)c2ccccc12)c1c(C)n(CC)c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
KDM4E B2RXH2 5/20 0.49
HPGD P15428 3/20 0.49
POLB P06746 1/20 0.49
MEN1 O00255 3/20 0.46
MAPT P10636 3/20 0.46
KMT2A Q03164 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
HTT P42858 2/20 0.46
NSD2 O96028 1/20 0.46
HSD17B10 Q99714 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CNR2 P34972 11/20 0.46
CNR1 P21554 8/20 0.46
CYP1A2 P05177 2/20 0.46
TSHR P16473 2/20 0.46
MAPK1 P28482 2/20 0.46
CYP2C19 P33261 2/20 0.46
NR1I2 O75469 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7477578 0.91 KDM4E (0.48) ALDH1A1KDM4EHPGDPOLBMEN1
SCHEMBL9416230 0.89 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDPOLBMEN1
SCHEMBL7484951 0.88 CNR2 (0.46) ALDH1A1KDM4EHPGDPOLBMEN1
SCHEMBL7485699 0.88 CNR2 (0.45) ALDH1A1KDM4EHPGDPOLBMEN1
SCHEMBL9581199 0.87 TSHR (0.46) ALDH1A1HPGDMEN1MAPTKMT2A
SCHEMBL9581071 0.86 CNR2 (0.45) ALDH1A1KDM4EHPGDPOLBMEN1
SCHEMBL7481996 0.85 CNR2 (0.47) ALDH1A1KDM4EHPGDPOLBMEN1
SCHEMBL7480384 0.84 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDPOLBMEN1
SCHEMBL9581198 0.84 KDM4E (0.40) ALDH1A1KDM4EHPGDPOLBMEN1
SCHEMBL10436262 0.84 CNR2 (0.62) CNR2CNR1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0386992-A2 Colour formers for recording sheets APPLETON PAPERS INC. (US) 1990-09-12 EP claimed
CN-107636085-B Aqueous inkjet ink 爱克发-格法特公司 2021-07-02 CN disclosed
US-10767063-B2 Aqueous inkjet inks AGFA-GEVAERT NV (BE) 2020-09-08 US disclosed
US-10767063-B2 Aqueous inkjet inks AGFA-GEVAERT NV (BE) 2020-09-08 US disclosed
CN-107580555-B It can laser labelling composition, product and file 爱克发-格法特公司 2019-11-05 CN disclosed
EP-3095825-B1 AQUEOUS INKJET INKS AGFA GEVAERT NV (BE) 2019-10-02 EP disclosed
US-20180345709-A1 LASER MARKABLE COMPOSITIONS AND METHODS TO MANUFACTURE A PACKAGING THEREWITH AGFA-GEVAERT (BE) 2018-12-06 US disclosed
US-10144239-B2 Laser markable compositions, articles and documents AGFA-GEVAERT (BE) 2018-12-04 US disclosed
US-20180201798-A1 AQUEOUS INKJET INKS AGFA-GEVAERT (BE) 2018-07-19 US disclosed
US-20180201798-A1 AQUEOUS INKJET INKS AGFA-GEVAERT (BE) 2018-07-19 US disclosed
EP-0465403-A1 Pressure sensitive recording and transfer material CIBA-GEIGY AG (CH) 1992-01-08 EP disclosed
EP-0463987-A1 Pressure sensitive recording material CIBA-GEIGY AG (CH) 1992-01-02 EP disclosed
US-5024988-A Color reaction system comprising a polycyclic heterocyclic compound, a leuko dye to form a chromogen with the first compound, a Lewis acid and developer CIBA-GEIGY CORPORATION (US) 1991-06-18 US disclosed
US-5001105-A Bis-(indoly)ethylenes record systems utilizing such compounds APPLETON PAPERS INC. (US) 1991-03-19 US disclosed
US-4996328-A Chromogens APPLETON PAPERS INC. (US) 1991-02-26 US disclosed
EP-0386992-A2 Colour formers for recording sheets APPLETON PAPERS INC. (US) 1990-09-12 EP disclosed
EP-0373110-A2 Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY AG (CH) 1990-06-13 EP disclosed
US-4895958-A CHROMOGENS, IMAGES, PRESSURE SENSITIVE AND HEAT RESPONSIVE CARBONLESS DUPLICATING HILTON DAVIS CO. (US) 1990-01-23 US disclosed
US-4870050-A CARBONLESS COPIES HILTON DAVIS CO. (US) 1989-09-26 US disclosed
US-4795736-A AMINOPHENYL PHENYLSULFONYL PROPENE/1-/ HILTON DAVIS CO. (US) 1989-01-03 US disclosed