SCHEMBL7480384

SCHEMBL7480384

C=C(c1cccc(C)c1)c1c(C)n(CC)c2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
KDM4E B2RXH2 5/20 0.45
MAPT P10636 5/20 0.45
HPGD P15428 4/20 0.45
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CNR2 P34972 5/20 0.44
CNR1 P21554 3/20 0.43
MAPK1 P28482 3/20 0.43
CYP1A2 P05177 2/20 0.43
TSHR P16473 2/20 0.43
CYP2C19 P33261 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
GMNN O75496 1/20 0.43
CYP3A4 P08684 1/20 0.43
ALOX15 P16050 1/20 0.43
NFKB1 P19838 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
BLM P54132 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7477578 0.88 KDM4E (0.48) ALDH1A1KDM4EMAPTHPGDLMNA
SCHEMBL7485699 0.85 CNR2 (0.45) ALDH1A1KDM4EMAPTHPGDLMNA
SCHEMBL6944584 0.84 ALDH1A1 (0.49) ALDH1A1KDM4EMAPTHPGDLMNA
SCHEMBL7481996 0.80 CNR2 (0.47) ALDH1A1KDM4EMAPTHPGDLMNA
SCHEMBL7487744 0.78 KDM4E (0.53) KDM4EMAPTHPGDLMNACNR2
SCHEMBL7480564 0.78 MEN1 (0.48) ALDH1A1KDM4EMAPTHPGDLMNA
SCHEMBL7484951 0.77 CNR2 (0.46) ALDH1A1KDM4EMAPTHPGDLMNA
SCHEMBL5972720 0.76 KDM4E (0.49) ALDH1A1KDM4EMAPTHPGDLMNA
SCHEMBL9416230 0.75 ALDH1A1 (0.64) ALDH1A1KDM4EMAPTHPGDLMNA
SCHEMBL9581199 0.74 TSHR (0.46) ALDH1A1MAPTHPGDLMNACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0664292-B1 A phtalide compound and a near infrared absorber and a recording material each comprising the same compound YAMAMOTO CHEMICALS INC (JP) 2002-06-19 EP disclosed
US-5627287-A COLORLESS YAMAMOTO CHEMICALS, INC. (JP) 1997-05-06 US disclosed
EP-0664292-A1 A phtalide compound and a near infrared absorber and a recording material each comprising the same compound YAMAMOTO CHEMICALS, INC. (JP) 1995-07-26 EP disclosed