Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11463318 | 0.80 | TP53 (0.69) | TP53TSHRGRIA4SIGMAR1EPHX1 | |
| SCHEMBL6948447 | 0.78 | KCNH2 (0.55) | TP53TSHRKCNH2GRIA4SIGMAR1 | |
| SCHEMBL19894770 | 0.77 | TP53 (0.69) | TP53TSHRKCNH2GRIA4SIGMAR1 | |
| SCHEMBL7873381 | 0.76 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL13778186 | 0.73 | NR1H4 (0.48) | TP53TSHRKCNH2GRIA4LMNA | |
| SCHEMBL31573982 | 0.73 | KCNH2 (0.67) | TP53TSHRKCNH2GRIA4SIGMAR1 | |
| SCHEMBL1068676 | 0.73 | KCNH2 (0.53) | TP53TSHRKCNH2GRIA4SIGMAR1 | |
| SCHEMBL13008878 | 0.72 | NR1H4 (0.50) | KCNH2SIGMAR1LMNAESRRGNR1H4 | |
| SCHEMBL10597831 | 0.72 | KCNH2 (0.49) | TP53TSHRKCNH2GRIA4SIGMAR1 | |
| SCHEMBL115558 | 0.72 | KCNH2 (0.49) | TP53TSHRKCNH2GRIA4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |