SCHEMBL6945229

SCHEMBL6945229

CC(=O)SC1CN(c2nc(C(=O)N(C)CCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cs2)C1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMYD2 Q9NRG4 3/20 0.34
CYP3A4 P08684 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
OGA O60502 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5725099 0.87 SMYD2 (0.33) SMYD2CYP3A4HTTSMN1; SMN2OGA
SCHEMBL5724508 0.86 OGA (0.33) OGA
SCHEMBL6944708 0.84 ACKR3 (0.37) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL6945233 0.82 OGA (0.34) OGA
SCHEMBL6949594 0.82 SMYD2 (0.32) SMYD2
SCHEMBL5724413 0.80 SMYD2 (0.32) SMYD2
SCHEMBL6949588 0.80 PIN1 (0.33) SMYD2CYP3A4HTTSMN1; SMN2OGA
SCHEMBL5725109 0.79 SMYD2 (0.32) SMYD2
SCHEMBL5724127 0.78 SMO (0.34) OGA
SCHEMBL6945286 0.78 CNR1 (0.33) SMYD2OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 EP disclosed