Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724301 | 0.87 | HIF1A (0.37) | ACKR3HIF1AHPGDSSMYD2CYP3A4 | |
| SCHEMBL5724124 | 0.86 | OGA (0.33) | ACKR3HTT | |
| SCHEMBL6949588 | 0.86 | PIN1 (0.33) | ACKR3HPGDSSMYD2CYP3A4HTT | |
| SCHEMBL6945229 | 0.84 | SMYD2 (0.34) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL6945220 | 0.84 | CTSK (0.34) | ACKR3SMYD2ALPLALPIALPG | |
| SCHEMBL6945217 | 0.84 | CTSK (0.34) | ACKR3SMYD2ALPLALPIALPG | |
| SCHEMBL6945286 | 0.84 | CNR1 (0.33) | HPGDSSMYD2ALPLALPIALPG | |
| SCHEMBL7075647 | 0.84 | OGA (0.33) | HPGDSSMYD2ALPLALPIALPG | |
| SCHEMBL7075651 | 0.84 | OGA (0.33) | HPGDSSMYD2ALPLALPIALPG | |
| SCHEMBL5724409 | 0.82 | OGA (0.33) | SMYD2ALPLALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340757-A1 | 1-METHYLCARBAPENEM DERIVATIVES | Sankyo Company, Limited (JP) | 2003-09-03 | — | — | EP | disclosed |