Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944540 | 1.00 | RORC (0.66) | RORCBDKRB2 | |
| SCHEMBL6942965 | 0.89 | BDKRB2 (0.54) | RORCBDKRB2 | |
| SCHEMBL6938693 | 0.88 | RORC (0.51) | RORCBDKRB2 | |
| SCHEMBL6946095 | 0.87 | BDKRB2 (0.53) | RORCBDKRB2 | |
| SCHEMBL7072602 | 0.81 | RORC (0.74) | RORCBDKRB2 | |
| SCHEMBL6945236 | 0.81 | RORC (0.86) | RORCBDKRB2 | |
| SCHEMBL6944528 | 0.81 | RORC (0.86) | RORCBDKRB2 | |
| SCHEMBL6938698 | 0.80 | RORC (0.73) | RORCBDKRB2 | |
| SCHEMBL7645405 | 0.80 | RORC (0.83) | RORCBDKRB2 | |
| SCHEMBL6946215 | 0.80 | RORC (0.85) | RORCBDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155013-B1 | HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2003-07-23 | — | — | EP | disclosed |
| US-6479515-B1 | FOR THE TREATMENT OF PAIN AND INFLAMMATION, AND ESPECIALLY IN THE TREATMENT OF ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-11-12 | — | — | US | disclosed |
| WO-2000050418-A9 | HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2001-02-22 | — | — | WO | disclosed |