Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943256 | 0.81 | SLC6A4 (0.70) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6947430 | 0.81 | SLC6A4 (0.66) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL6945836 | 0.81 | SLC6A4 (0.63) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL6945794 | 0.80 | SLC6A4 (0.69) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL6952018 | 0.78 | SLC6A4 (0.73) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL3364476 | 0.78 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3CACNA1B | |
| SCHEMBL13409793 | 0.78 | SLC6A4 (0.55) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL3363448 | 0.77 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL7211594 | 0.77 | SLC6A4 (0.69) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL6945663 | 0.76 | SLC6A4 (0.66) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475804-B2 | Compositions and methods for treatment of filovirus-mediated diseases | U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110028564-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | ZALICUS INC. | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028564-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | FLNA, FLNB, PIGS | SLC6A4 4537/4885HTR2A 4618/4885KCNH2 2148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.