Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945277 | 0.86 | CHEK1 (0.48) | CHEK1MAPTNPC1RAB9ABRD4 | |
| SCHEMBL29828622 | 0.86 | CHEK1 (0.48) | CHEK1MAPTNPC1RAB9ABRD4 | |
| SCHEMBL6943101 | 0.86 | RAB9A (0.50) | MAPTNPC1RAB9ABRD4CREBBP | |
| SCHEMBL6950391 | 0.85 | CHEK1 (0.52) | CHEK1MAPTNPC1RAB9ABRD4 | |
| Hydrochloric Acid SCHEMBL6953890 | 0.84 | CHEK1 (0.51) | CHEK1MAPTNPC1RAB9ABRD4 | |
| SCHEMBL6945580 | 0.82 | MAPT (0.45) | MAPTNPC1RAB9AHSD17B10MMP2 | |
| SCHEMBL6950164 | 0.81 | TP53 (0.47) | RAB9AMMP2ALDH1A1KMT2A | |
| SCHEMBL6943129 | 0.81 | TP53 (0.47) | RAB9AMMP2ALDH1A1KMT2A | |
| SCHEMBL6954316 | 0.81 | CHEK1 (0.45) | CHEK1MAPTNPC1RAB9ABRD4 | |
| SCHEMBL6949858 | 0.81 | CHEK1 (0.41) | CHEK1MAPTNPC1RAB9ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |