Sugi Predict

Sugi Predict / Compounds / SCHEMBL6945643

SCHEMBL6945643

SCHEMBL6945643

O=C(Cc1nc[nH]n1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 3/20 0.46
▸ MAPT P10636 5/20 0.45
▸ TDP1 Q9NUW8 3/20 0.45
▸ CYP3A4 P08684 3/20 0.45
▸ MEN1 O00255 3/20 0.45
▸ KMT2A Q03164 3/20 0.45
▸ SMN1; SMN2 Q16637 3/20 0.45
▸ KDM4E B2RXH2 2/20 0.45
▸ MAPK1 P28482 2/20 0.45
▸ ALOX15 P16050 1/20 0.45
▸ CES1 P23141 1/20 0.45
▸ GLA P06280 1/20 0.45
▸ CTNNB1 P35222 2/20 0.43
▸ WNT3A P56704 2/20 0.43
▸ L3MBTL1 Q9Y468 5/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ GSK3B P49841 2/20 0.42
▸ HIF1A Q16665 2/20 0.42
▸ TRPA1 O75762 1/20 0.42
▸ PTPN1 P18031 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11017231 0.90 MAPT (0.49) HPGDMAPTTDP1SMN1; SMN2KDM4E
SCHEMBL9458106 0.88 ERCC5 (0.51) MAPTSMN1; SMN2ALOX15ALDH1A1NPC1
SCHEMBL9667197 0.83 NPC1 (0.50) HPGDMAPTMEN1KMT2ASMN1; SMN2
SCHEMBL9875118 0.79 PTPN1 (0.50) MAPTMEN1KMT2ACES1ALDH1A1
Hydrochloric Acid SCHEMBL3647522 0.77 GSK3B (0.50) MAPTTDP1MEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL2170718 0.75 ALDH1A1 (0.42) MAPTCYP3A4KDM4EALOX15ALDH1A1
Water SCHEMBL10651493 0.75 HTT (0.38) HPGDMAPTTDP1MEN1KMT2A
SCHEMBL1449520 0.74 HTT (0.65) HPGDMAPTTDP1CYP3A4MEN1
SCHEMBL10986702 0.73 ALDH1A1 (0.57) HPGDMAPTCYP3A4MEN1KMT2A
SCHEMBL6203299 0.73 NPC1 (0.51) HPGDCYP3A4MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116589419-A 2-phenoxy-2- (1H-1, 2, 4-triazole) -acetophenone compound and preparation method and application thereof 中国农业大学 2023-08-15 — — CN claimed
JP-62135466-A — — None — — JP disclosed
CN-116589419-A 2-phenoxy-2- (1H-1, 2, 4-triazole) -acetophenone compound and preparation method and application thereof 中国农业大学 2023-08-15 — — CN disclosed
EP-3491922-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO Dow AgroSciences LLC (US) 2019-06-05 — — EP disclosed
EP-2934118-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-01-31 — — EP disclosed
EP-2934142-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-01-31 — — EP disclosed
EP-2934135-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-01-31 — — EP disclosed
US-20170267629-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2017-09-21 — — US disclosed
US-9701620-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-07-11 — — US disclosed
US-20170156320-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2017-06-08 — — US disclosed
WO-2012177813-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-12-27 — — WO disclosed
US-20120329649-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC 2012-12-27 — — US disclosed
US-6649568-B2 1,2,4-triazolyl-alcohols; plant growth regulators RIKEN (JP) 2003-11-18 — — US disclosed
US-20030166468-A1 Brassinosteroid biosynthesis inhibitor RIKEN (JP) 2003-09-04 — — US disclosed
EP-1270561-A1 BRASSINOSTEROID BIOSYNTHESIS INHIBITOR RIKEN (JP) 2003-01-02 — — EP disclosed
US-4940806-A Microbicides CIBA-GEIGY CORPORATION (US) 1990-07-10 — — US disclosed
US-4940806-A Microbicides CIBA-GEIGY CORPORATION (US) 1990-07-10 — — US disclosed
US-4853399-A Microbicidal triazolyl phenylethanone ketals CIBA-GEIGY CORPORATION (US) 1989-08-01 — — US disclosed
US-4853399-A Microbicidal triazolyl phenylethanone ketals CIBA-GEIGY CORPORATION (US) 1989-08-01 — — US disclosed
JP-S62135466-A HALOALKOXY SUBSTITUTED 2-(1H-1,2,4-TRIAZOLYL)-1-PHENYLETHANE-1-ONE KETAL, MANUFACTURE AND MICROBICIDE CONTAINING SAME CIBA GEIGY AG 1987-06-18 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267629-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS HPGD 1459/4885MAPT 3589/4885TDP1 2276/4885
US-20120329649-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS HPGD 1459/4885MAPT 3589/4885TDP1 2276/4885
US-20170156320-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS HPGD 1459/4885MAPT 3589/4885TDP1 2276/4885
US-20030166468-A1 Brassinosteroid biosynthesis inhibitor BRI3BP, CYP51A1, BRD1 HPGD 2446/4885MAPT 4289/4885TDP1 4227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.