Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624172 | 0.81 | CASP3 (0.74) | CASP3SENP7SENP6L3MBTL1HSD17B10 | |
| SCHEMBL11624176 | 0.81 | CASP3 (0.74) | CASP3SENP7SENP6L3MBTL1HSD17B10 | |
| SCHEMBL8722404 | 0.77 | CASP3 (0.53) | CASP3SENP7SENP6L3MBTL1HSD17B10 | |
| SCHEMBL6945791 | 0.77 | CASP3 (0.53) | CASP3SENP7SENP6L3MBTL1HSD17B10 | |
| SCHEMBL19196836 | 0.77 | SMN1; SMN2 (0.49) | CASP3SENP7SENP6L3MBTL1HSD17B10 | |
| SCHEMBL11709281 | 0.76 | TP53 (0.48) | CASP3SENP7SENP6L3MBTL1HSD17B10 | |
| SCHEMBL13655841 | 0.74 | TP53 (0.35) | CASP3SENP7SENP6L3MBTL1HSD17B10 | |
| SCHEMBL3336657 | 0.73 | MAPT (0.58) | L3MBTL1HSD17B10ALDH1A1HPGDALOX15 | |
| SCHEMBL16118325 | 0.72 | CASP3 (0.49) | CASP3SENP7SENP6L3MBTL1HSD17B10 | |
| SCHEMBL12440436 | 0.71 | TP53 (0.48) | HSD17B10TSHRALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261587-B1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | UNIV BASEL (CH) | 2003-07-16 | — | — | EP | claimed |
| EP-1261587-A1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | Universität Basel (CH) | 2002-12-04 | — | — | EP | claimed |
| WO-2001040194-A1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT BASEL (CH) | 2001-06-07 | — | — | WO | claimed |
| EP-1261587-B1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | UNIV BASEL (CH) | 2003-07-16 | — | — | EP | disclosed |
| EP-1261587-A1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | Universität Basel (CH) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001040194-A1 | STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT BASEL (CH) | 2001-06-07 | — | — | WO | disclosed |