SCHEMBL69458

SCHEMBL69458

O=C(Oc1ccccc1)c1cccc(C(=O)Oc2ccccc2)n1

nearest known ligand 0.75

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.75
ALDH1A1 P00352 5/20 0.70
CYP1A2 P05177 2/20 0.58
GAA P10253 2/20 0.58
RECQL P46063 1/20 0.58
KDM4E B2RXH2 5/20 0.56
TDP1 Q9NUW8 4/20 0.56
ALOX15 P16050 2/20 0.52
TSHR P16473 1/20 0.52
ACMSD Q8TDX5 1/20 0.52
HSD17B10 Q99714 2/20 0.50
HPGD P15428 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NSD2 O96028 1/20 0.47
POLB P06746 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7236760 0.87 MAPT (0.60) MAPTALDH1A1CYP1A2GAARECQL
SCHEMBL31432684 0.86 ALDH1A1 (0.63) MAPTALDH1A1CYP1A2GAARECQL
SCHEMBL30185288 0.80 MAPT (0.69) MAPTALDH1A1GAAKDM4ETDP1
SCHEMBL3961211 0.80 MAPT (0.69) MAPTALDH1A1GAAKDM4ETDP1
SCHEMBL28130309 0.80 KDM4E (0.69) MAPTALDH1A1GAAKDM4ETDP1
SCHEMBL68414 0.79 TDP1 (0.66) MAPTALDH1A1KDM4ETDP1ALOX15
SCHEMBL8943412 0.77 MAPT (0.50) MAPTALDH1A1KDM4ETDP1ALOX15
SCHEMBL8587424 0.77 MAPT (0.50) MAPTALDH1A1CYP1A2GAARECQL
SCHEMBL24218417 0.76 ALDH1A1 (0.64) MAPTALDH1A1GAAKDM4ETDP1
SCHEMBL15300224 0.75 MAPT (0.47) MAPTALDH1A1KDM4ETDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113292722-A Preparation method of polybenzimidazole polymer with high molecular weight and high solubility 中国科学院上海有机化学研究所 2021-08-24 CN disclosed
CN-113292729-A Preparation method of high-solubility polybenzimidazole copolymer 中国科学院上海有机化学研究所 2021-08-24 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885ALDH1A1 1882/4885CYP1A2 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.