Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 6/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 6/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091021 | 0.99 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53CACNA1FCACNA1DCACNA1S | |
| SCHEMBL6948567 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2TP53MEN1KMT2APDE1C | |
| SCHEMBL6953510 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2TP53MEN1KMT2ACYP1A2 | |
| SCHEMBL8099097 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53MEN1KMT2APDE1C | |
| SCHEMBL8091377 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53MEN1KMT2APDE1C | |
| SCHEMBL6942333 | 0.76 | CACNA1F (0.49) | TP53CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6942341 | 0.76 | CACNA1F (0.49) | TP53CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3032439 | 0.75 | MTOR (0.59) | SMN1; SMN2TP53CACNA1CMEN1KMT2A | |
| SCHEMBL13285115 | 0.74 | CYP2C9 (0.67) | TP53CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6942347 | 0.74 | CACNA1F (0.47) | TP53CACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657431-B1 | 4-Phenyl-3-substituted 1,4-dihydropyridine esters with cerebral activity | BAYER AG (DE) | 2003-02-19 | — | — | EP | claimed |
| US-6066655-A | FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, IN PARTICULAR AS CEREBRAL THERAPEUTICS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-23 | — | — | US | disclosed |
| US-5731333-A | LEARNING AND MEMORY ENHANCEMENT, ANTIDEPRESSANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |