Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | MTOR | P42345 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3032439 | 0.95 | MTOR (0.59) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7884089 | 0.92 | NR1I2 (0.59) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 | |
| SCHEMBL2615067 | 0.90 | CYP2C9 (0.67) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 | |
| SCHEMBL2615068 | 0.88 | CYP2C9 (0.79) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13285114 | 0.88 | CYP2C9 (0.79) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7154933 | 0.87 | MTOR (0.62) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 | |
| SCHEMBL8913648 | 0.87 | ADORA3 (0.52) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 | |
| SCHEMBL3027183 | 0.84 | ADORA3 (0.59) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 | |
| SCHEMBL6945817 | 0.82 | ALOX15 (0.51) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7348030 | 0.82 | ADORA3 (0.58) | CYP2C9HIF1AMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081036-A2 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-07-15 | — | — | WO | disclosed |