Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694623 | 1.00 | ITGB3 (0.51) | ITGB3ITGA2BP2RY12P2RX7TGM2 | |
| SCHEMBL3720732 | 0.90 | P2RY12 (0.52) | ITGB3ITGA2BP2RY12P2RX7TGM2 | |
| SCHEMBL317118 | 0.88 | P2RX7 (0.56) | P2RY12P2RX7BCHEACHE | |
| SCHEMBL317119 | 0.88 | P2RX7 (0.56) | P2RY12P2RX7BCHEACHE | |
| SCHEMBL951528 | 0.85 | P2RY12 (0.55) | P2RY12P2RX7 | |
| SCHEMBL951526 | 0.85 | P2RY12 (0.55) | P2RY12P2RX7 | |
| SCHEMBL317465 | 0.84 | P2RY12 (0.59) | P2RY12P2RX7 | |
| SCHEMBL317464 | 0.84 | P2RY12 (0.59) | P2RY12P2RX7 | |
| SCHEMBL954484 | 0.83 | P2RX7 (0.51) | ITGB3ITGA2BP2RY12P2RX7BCHE | |
| SCHEMBL954482 | 0.83 | P2RX7 (0.51) | ITGB3ITGA2BP2RY12P2RX7BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421859-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-02-29 | — | — | EP | disclosed |