Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944020 | 0.88 | PKM (0.66) | KMT2AHPGDALDH1A1KDM4EPKM | |
| SCHEMBL1435186 | 0.81 | HDAC1 (0.64) | KMT2AHPGDMEN1LMNAERCC1 | |
| SCHEMBL2413773 | 0.81 | HDAC1 (0.65) | NAMPT | |
| SCHEMBL1749879 | 0.80 | NR4A2 (0.59) | NPSR1SMN1; SMN2 | |
| SCHEMBL6204996 | 0.78 | NR4A2 (0.65) | KMT2AMEN1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL1566393 | 0.77 | CYP3A4 (0.73) | KMT2AHPGDALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2412851 | 0.77 | NAMPT (0.60) | KMT2AMEN1ALDH1A1LMNANAMPT | |
| SCHEMBL2412396 | 0.76 | HDAC1 (0.70) | — | |
| SCHEMBL9787292 | 0.76 | LSS (0.70) | KMT2AHPGDMEN1ALDH1A1KDM4E | |
| SCHEMBL1567098 | 0.76 | NAMPT (0.67) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974576-B1 | Method of producing benzamide derivatives | MITSUI CHEMICALS INC (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6320078-B1 | CONVERTING BENZOIC ACID DERIVATIVE INTO BENZOYLIMIDAZOLE DERIVATIVE, REACTING BENZOYLIMIDAZOLE DERIVATIVE WITH PHENYLENEDIAMINE DERIVATIVE TO PREPARE SELECTIVELY MONOACYLATED PHENYLENEDIAMINE DERIVATIVE | MITSUI CHEMICALS, INC. (JP) | 2001-11-20 | — | — | US | disclosed |
| EP-0974576-A2 | Method of producing benzamide derivatives | Mitsui Chemicals, Inc. (JP) | 2000-01-26 | — | — | EP | disclosed |