Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951793 | 0.88 | MAPT (0.38) | MAPTHSD17B10CHEK1HDAC1BRD4 | |
| Hydrochloric Acid SCHEMBL6949932 | 0.88 | MAPT (0.42) | MAPTTDP1L3MBTL1HSD17B10CHEK1 | |
| SCHEMBL6951801 | 0.88 | MAPT (0.42) | MAPTNTRK1HSD17B10CHEK1HDAC1 | |
| SCHEMBL6945277 | 0.85 | CHEK1 (0.48) | MAPTNTRK1HSD17B10CHEK1HDAC1 | |
| SCHEMBL29828622 | 0.85 | CHEK1 (0.48) | MAPTNTRK1HSD17B10CHEK1HDAC1 | |
| SCHEMBL6946457 | 0.85 | MAPT (0.41) | MAPTTDP1L3MBTL1NTRK1HSD17B10 | |
| SCHEMBL6950177 | 0.81 | MAPT (0.43) | MAPTTDP1L3MBTL1NTRK1HSD17B10 | |
| SCHEMBL6950391 | 0.78 | CHEK1 (0.52) | MAPTNTRK1HSD17B10CHEK1BRD4 | |
| SCHEMBL6948766 | 0.78 | CHEK1 (0.47) | MAPTNTRK1HSD17B10CHEK1HDAC1 | |
| SCHEMBL7653156 | 0.78 | ALDH1A1 (0.42) | MAPTTDP1NTRK1HSD17B10CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |