Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 8/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744200 | 0.89 | CA1 (0.50) | CA1CA2CA7KMT2ACA12 | |
| SCHEMBL23607312 | 0.83 | CA1 (0.52) | CA1CA2CA7KMT2ACA12 | |
| SCHEMBL1689249 | 0.83 | CA1 (0.52) | CA1CA2CA7KMT2ACA12 | |
| SCHEMBL23849248 | 0.83 | CA1 (0.52) | CA1CA2CA7KMT2ACA12 | |
| SCHEMBL19209667 | 0.81 | CA1 (0.45) | CA1CA2CA7KMT2ACA12 | |
| SCHEMBL709981 | 0.81 | CA14 (0.59) | CA1CA2CA7KMT2ACA12 | |
| SCHEMBL2380555 | 0.81 | CA14 (0.59) | CA1CA2CA7KMT2ACA12 | |
| SCHEMBL241988 | 0.81 | CA14 (0.59) | CA1CA2CA7KMT2ACA12 | |
| Hydrochloric Acid SCHEMBL29367798 | 0.79 | CA14 (0.57) | CA1CA2CA7KMT2ACA12 | |
| SCHEMBL28851533 | 0.78 | CA1 (0.47) | CA1CA2CA7KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847994-B1 | Process for the preparation of mixed anhydrides | HOFFMANN LA ROCHE (CH) | 2003-04-09 | — | — | EP | claimed |
| US-20020077481-A1 | Process for the preparation of mixed anhydrides | KARPF MARTIN (CH) | 2002-06-20 | — | — | US | claimed |
| US-20240368125-A1 | NOVEL PYRAZINYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-11-07 | — | — | US | disclosed |
| EP-2385050-A1 | A process for preparing a substituted oxazole | Schering Corporation (US) | 2011-11-09 | — | — | EP | disclosed |
| EP-2385051-A1 | Process for making a substituted oxazole | Schering Corporation (US) | 2011-11-09 | — | — | EP | disclosed |
| US-7985860-B2 | Process and intermediates for the synthesis of 2-(quinolin-5-yl)-4,5 disubstituted-azole derivatives | SCHERING CORPORATION (US) | 2011-07-26 | — | — | US | disclosed |
| US-7985860-B2 | Process and intermediates for the synthesis of 2-(quinolin-5-yl)-4,5 disubstituted-azole derivatives | SCHERING CORPORATION (US) | 2011-07-26 | — | — | US | disclosed |
| US-20100324295-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 5-QUINOLYL-OXAZOLES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | SCHERING CORPORATION | 2010-12-23 | — | — | US | disclosed |
| US-20100324295-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 5-QUINOLYL-OXAZOLES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | SCHERING CORPORATION | 2010-12-23 | — | — | US | disclosed |
| US-20080045718-A1 | Process and intermediates for the synthesis of 2-(quinolin-5-yl)-4,5 disubstituted-azole derivatives | MERCK SHARP & DOHME CORP. | 2008-02-21 | — | — | US | disclosed |
| US-20080045718-A1 | Process and intermediates for the synthesis of 2-(quinolin-5-yl)-4,5 disubstituted-azole derivatives | MERCK SHARP & DOHME CORP. | 2008-02-21 | — | — | US | disclosed |
| US-6562977-B2 | For use in the synthesis of peptides and/or for the manufacture of pharmaceutically active substances or corresponding intermediates | HOFFMANN-LA ROCHE INC. | 2003-05-13 | — | — | US | disclosed |
| US-6489479-B1 | THE PRESENT INVENTION IS CONCERNED WITH AN IMPROVED PROCESS FOR THE MANUFACTURE OF MIXED ANHYDRIDES. THE PROCESS COMPRISES ADDING AN ADJUVANT BASE TO A MIXTURE OF ACID AND REACTIVE ACID DERIVATIVE. IT IS ESPECIALLY SUITABLE FOR USE IN THE | HOFFMAN-LA ROCHE INC. | 2002-12-03 | — | — | US | disclosed |
| US-20020077481-A1 | Process for the preparation of mixed anhydrides | KARPF MARTIN (CH) | 2002-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324295-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 5-QUINOLYL-OXAZOLES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | PDE4B, PDE4A, PDE3B | CA1 2985/4885CA2 876/4885CA7 425/4885 |
| US-20020077481-A1 | Process for the preparation of mixed anhydrides | CA1, CA14, CA12 | CA1 1/4885CA2 9/4885CA7 5/4885 |
| US-20240368125-A1 | NOVEL PYRAZINYL-TRIAZOLE COMPOUNDS AS PESTICIDES | PRDX1, PRDX5, PRXL2A | CA1 4244/4885CA2 4128/4885CA7 4687/4885 |
| US-20080045718-A1 | Process and intermediates for the synthesis of 2-(quinolin-5-yl)-4,5 disubstituted-azole derivatives | PDE4B, PDE4A, PDE3B | CA1 2955/4885CA2 491/4885CA7 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.