Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524035 | 0.90 | ALDH1A1 (0.59) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL5480680 | 0.82 | SLC2A1 (0.53) | ALDH1A1TSHRTDP1TP53 | |
| SCHEMBL7639 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1HDAC8TAS1R3 | |
| SCHEMBL473081 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1HDAC8TAS1R3 | |
| SCHEMBL30083976 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1HDAC8TYR | |
| SCHEMBL19273327 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1HDAC8TYR | |
| SCHEMBL8992223 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1HDAC8TYR | |
| SCHEMBL17249485 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL1264527 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8TYR | |
| SCHEMBL367595 | 0.78 | TYR (0.58) | ALDH1A1TSHRTDP1HDAC8TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003104304-A1 | METHOD FOR MAKING SILOXANE POLYMERS | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2003-12-18 | — | — | WO | disclosed |
| US-20030232951-A1 | Preparation of low loss optical material from difunctional silyl enol ethers and difunctional silanols | AUSTRALIAN NATIONAL UNIVERSITY, THE (AU) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232951-A1 | Preparation of low loss optical material from difunctional silyl enol ethers and difunctional silanols | CNKSR1, CCNL2, SAAL1 | ALDH1A1 461/4885TSHR 3837/4885TDP1 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.