⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167374 | 1.00 | — | — | |
| SCHEMBL29116197 | 0.97 | — | — | |
| SCHEMBL29034419 | 0.97 | ALDH1A1 (0.40) | — | |
| SCHEMBL1961611 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL2160220 | 0.97 | — | — | |
| SCHEMBL1959272 | 0.97 | — | — | |
| SCHEMBL29116204 | 0.97 | — | — | |
| SCHEMBL1962788 | 0.97 | — | — | |
| Formamide SCHEMBL716210 | 0.90 | ALDH1A1 (0.35) | — | |
| SCHEMBL28269767 | 0.90 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158972-A4 | TREATMENT OF HYPERTENSION WITH COMPOUNDS THAT INHIBIT THE DESTRUCTION OF ENKEPHALINS OR ENDORPHINS | EHRENPREIS SEYMOUR (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1158972-A1 | TREATMENT OF HYPERTENSION WITH COMPOUNDS THAT INHIBIT THE DESTRUCTION OF ENKEPHALINS OR ENDORPHINS | Ehrenpreis, Seymour (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000041686-A1 | TREATMENT OF HYPERTENSION WITH COMPOUNDS THAT INHIBIT THE DESTRUCTION OF ENKEPHALINS OR ENDORPHINS | EHRENPREIS SEYMOUR (US) | 2000-07-20 | — | — | WO | disclosed |