Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.59 |
| ▸ | NQO2 | P16083 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26619104 | 0.76 | ATM (0.54) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL30644025 | 0.76 | ATM (0.54) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL8688610 | 0.74 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL18800052 | 0.74 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL15428004 | 0.73 | NQO2 (1.00) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL28649300 | 0.73 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL6193835 | 0.72 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL29134983 | 0.71 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL30704310 | 0.71 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL23950124 | 0.71 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851855-B9 | ACYLATED DERIVATIVES OF MELATONIN AND ITS ANALOGUES, USEFUL AS MEDICAMENTS | MACEF (FR) | 2003-05-21 | — | — | EP | claimed |
| EP-0851855-B1 | ACYLATED DERIVATIVES OF MELATONIN AND ITS ANALOGUES, USEFUL AS MEDICAMENTS | MACEF (FR) | 2002-06-05 | — | — | EP | claimed |
| EP-0851855-B9 | ACYLATED DERIVATIVES OF MELATONIN AND ITS ANALOGUES, USEFUL AS MEDICAMENTS | MACEF (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-0851855-B1 | ACYLATED DERIVATIVES OF MELATONIN AND ITS ANALOGUES, USEFUL AS MEDICAMENTS | MACEF (FR) | 2002-06-05 | — | — | EP | disclosed |
| US-6140372-A | N-(2-(2-ACETYL-7-METHOXYNAPHTH-1-YL)ETHYL)ACETAMIDE; SEDATIVES; MELATONIN DISORDERS; DRUGS; COSMETICS; ANTIDEPRESSANTS; PSYCHIATRIC DISORDERS, E.G., STRESS, ANXIOLYTIC AGENTS, INSOMNIA, SCHIZOPHRENIA, PSYCHOSIS | CEMAF AND LABORATORIES BESINS ISOVESCO S.A. (FR) | 2000-10-31 | — | — | US | disclosed |
| US-6004991-A | COMPOUNDS FOR COSMETICS WITH ENANTIOMORPHS | CEMAF AND LABORATOIRES BESINS ISCOVESCO S.A. (FR) | 1999-12-21 | — | — | US | disclosed |
| EP-0851855-A1 | ACYLATED DERIVATIVES OF MELATONIN AND ITS ANALOGUES, USEFUL AS MEDICAMENTS | CEMAF (FR) | 1998-07-08 | — | — | EP | disclosed |
| WO-1997006140-A1 | ACYLATED DERIVATIVES OF MELATONIN AND ITS ANALOGUES, USEFUL AS MEDICAMENTS | CEMAF (FR) | 1997-02-20 | — | — | WO | disclosed |