Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.64 |
| ▸ | NQO2 | P16083 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18800026 | 0.89 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL18800012 | 0.89 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL18800030 | 0.87 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL18800058 | 0.86 | MTNR1A (0.48) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL18800048 | 0.85 | SPR (0.52) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL18800091 | 0.83 | MTNR1A (0.46) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL18800029 | 0.83 | MTNR1A (0.46) | MTNR1AMTNR1BNQO2ALDH1A1 | |
| SCHEMBL18800060 | 0.82 | MTNR1A (0.45) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL18800090 | 0.81 | HTR2B (0.52) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL18800006 | 0.80 | MTNR1A (0.45) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637451-B2 | Indole compound | ASTELLAS PHARMA INC. (JP) | 2017-05-02 | — | — | US | disclosed |