Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 1.00 |
| ▸ | ITGA2B | P08514 | 16/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285318 | 1.00 | ITGB3 (1.00) | ITGB3ITGA2BPOLB | |
| SCHEMBL6947214 | 1.00 | ITGB3 (1.00) | ITGB3ITGA2BPOLB | |
| SCHEMBL7285305 | 1.00 | ITGB3 (1.00) | ITGB3ITGA2BPOLB | |
| SCHEMBL8379150 | 0.91 | ITGB3 (0.82) | ITGB3ITGA2BPOLB | |
| SCHEMBL8379143 | 0.91 | ITGB3 (0.82) | ITGB3ITGA2BPOLB | |
| SCHEMBL8379159 | 0.91 | ITGB3 (0.82) | ITGB3ITGA2BPOLB | |
| SCHEMBL8379170 | 0.91 | ITGB3 (0.82) | ITGB3ITGA2BPOLB | |
| SCHEMBL8379356 | 0.90 | ITGB3 (0.81) | ITGB3ITGA2BPOLB | |
| SCHEMBL8379329 | 0.90 | ITGB3 (0.81) | ITGB3ITGA2BPOLB | |
| SCHEMBL8379352 | 0.90 | ITGB3 (0.81) | ITGB3ITGA2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847994-B1 | Process for the preparation of mixed anhydrides | HOFFMANN LA ROCHE (CH) | 2003-04-09 | — | — | EP | claimed |
| EP-0656348-B1 | Aceric acid derivatives as medicaments | HOFFMANN LA ROCHE (CH) | 2000-05-03 | — | — | EP | claimed |
| US-6562977-B2 | For use in the synthesis of peptides and/or for the manufacture of pharmaceutically active substances or corresponding intermediates | HOFFMANN-LA ROCHE INC. | 2003-05-13 | — | — | US | disclosed |
| US-6489479-B1 | THE PRESENT INVENTION IS CONCERNED WITH AN IMPROVED PROCESS FOR THE MANUFACTURE OF MIXED ANHYDRIDES. THE PROCESS COMPRISES ADDING AN ADJUVANT BASE TO A MIXTURE OF ACID AND REACTIVE ACID DERIVATIVE. IT IS ESPECIALLY SUITABLE FOR USE IN THE | HOFFMAN-LA ROCHE INC. | 2002-12-03 | — | — | US | disclosed |
| US-20020077481-A1 | Process for the preparation of mixed anhydrides | KARPF MARTIN (CH) | 2002-06-20 | — | — | US | disclosed |
| EP-0656348-B1 | Aceric acid derivatives as medicaments | HOFFMANN LA ROCHE (CH) | 2000-05-03 | — | — | EP | disclosed |
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0656348-A2 | Aceric acid derivatives as medicaments | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077481-A1 | Process for the preparation of mixed anhydrides | CA1, CA14, CA12 | ITGB3 3219/4885ITGA2B 2007/4885POLB 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.