Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.81 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379356 | 1.00 | ITGB3 (0.81) | ITGB3ITGA2BPOLBMBOAT4SMYD3 | |
| SCHEMBL8379329 | 1.00 | ITGB3 (0.81) | ITGB3ITGA2BPOLBMBOAT4SMYD3 | |
| SCHEMBL8379343 | 1.00 | ITGB3 (0.81) | ITGB3ITGA2BPOLBMBOAT4SMYD3 | |
| SCHEMBL6947214 | 0.90 | ITGB3 (1.00) | ITGB3ITGA2BPOLB | |
| SCHEMBL7285318 | 0.90 | ITGB3 (1.00) | ITGB3ITGA2BPOLB | |
| SCHEMBL7285305 | 0.90 | ITGB3 (1.00) | ITGB3ITGA2BPOLB | |
| SCHEMBL6947203 | 0.90 | ITGB3 (1.00) | ITGB3ITGA2BPOLB | |
| SCHEMBL7274714 | 0.89 | ITGB3 (0.80) | ITGB3ITGA2B | |
| SCHEMBL8650403 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BPOLBMBOAT4SMYD3 | |
| SCHEMBL8379278 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2BMBOAT4SMYD3P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |