Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 9/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947286 | 1.00 | KDM4E (0.48) | KDM4ENPC1TSHRPAOXSUCNR1 | |
| SCHEMBL16364172 | 0.87 | KDM4E (0.41) | KDM4ENPC1TSHRPAOXSUCNR1 | |
| SCHEMBL9805779 | 0.85 | KDM4E (0.46) | KDM4ENPC1TSHRPAOXSUCNR1 | |
| SCHEMBL9805775 | 0.85 | KDM4E (0.46) | KDM4ENPC1TSHRPAOXSUCNR1 | |
| SCHEMBL28290388 | 0.83 | FOLH1 (0.46) | KDM4ENPC1KDM4AKDM4CKDM5A | |
| SCHEMBL28290386 | 0.83 | FOLH1 (0.46) | KDM4ENPC1KDM4AKDM4CKDM5A | |
| SCHEMBL2907971 | 0.82 | CA2 (0.42) | TSHR | |
| SCHEMBL6544634 | 0.82 | CA2 (0.42) | TSHR | |
| SCHEMBL2129750 | 0.82 | CA2 (0.42) | TSHR | |
| SCHEMBL11234189 | 0.81 | KDM4E (0.43) | KDM4ENPC1TSHRPAOXKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026915-A | FABRIC SOFTENERS | S. C. JOHNSON & SON, INC. (US) | 1977-05-31 | — | — | US | claimed |
| EP-0772771-B2 | DETERMINING BIODEGRADABILITY OF ASPARTIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | DOW CHEMICAL CO (US) | 2003-12-17 | — | — | EP | disclosed |
| EP-0772771-B1 | DETERMINING BIODEGRADABILITY OF ASPARTIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | DOW CHEMICAL CO (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0959352-A1 | Determining biodegradability of aspartic acid derivatives, degradable chelants, uses and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1999-11-24 | — | — | EP | disclosed |
| US-5854060-A | Determining biodegradability of aspartic acid derivatives, degradable chelants, uses and compositions | THE DOW CHEMICAL COMPANY (US) | 1998-12-29 | — | — | US | disclosed |
| US-5776763-A | Analytical process to determine biodegradability of chelants containing a double carboxy containing moiety | THE DOW CHEMICAL COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| US-4026915-A | FABRIC SOFTENERS | S. C. JOHNSON & SON, INC. (US) | 1977-05-31 | — | — | US | disclosed |