Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805775 | 1.00 | KDM4E (0.46) | KDM4ENPC1TSHRPAOXMAPK1 | |
| SCHEMBL11246906 | 0.90 | TSHR (0.39) | KDM4ENPC1TSHRMAPK1MEN1 | |
| SCHEMBL11234189 | 0.86 | KDM4E (0.43) | KDM4ENPC1TSHRPAOXHTT | |
| SCHEMBL11151811 | 0.86 | KDM4E (0.43) | KDM4ENPC1TSHRPAOXMAPK1 | |
| SCHEMBL6947286 | 0.85 | KDM4E (0.48) | KDM4ENPC1TSHRPAOXSUCNR1 | |
| SCHEMBL6947280 | 0.85 | KDM4E (0.48) | KDM4ENPC1TSHRPAOXSUCNR1 | |
| SCHEMBL11148996 | 0.84 | HTT (0.47) | KDM4ENPC1TSHRPAOXMAPK1 | |
| SCHEMBL11152622 | 0.83 | DNM1 (0.42) | KDM4ENPC1TSHRMAPK1DNM1 | |
| SCHEMBL8740356 | 0.80 | ALDH1A1 (0.41) | KDM4EKMT2ADNM1ALOX15SUCNR1 | |
| SCHEMBL11237882 | 0.80 | KDM4E (0.39) | KDM4ENPC1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022059-B1 | N-SUBSTITUTED ESTERS OF ASPARTIC ACID, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1983-08-17 | — | — | EP | claimed |
| US-4326069-A | CURING AGENTS FOR POLYEPOXIDES | CIBA-GEIGY CORPORATION (US) | 1982-04-20 | — | — | US | claimed |
| US-5032488-A | Method of metalizing a surface using a mixture of olefin and dibenzalacetone palladium complex | CIBA-GEIGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |
| US-4326069-A | CURING AGENTS FOR POLYEPOXIDES | CIBA-GEIGY CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |