Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | PPARG | P37231 | 16/20 | 0.63 |
| ▸ | PPARA | Q07869 | 16/20 | 0.63 |
| ▸ | PPARD | Q03181 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952459 | 0.92 | SMN1; SMN2 (0.66) | NPC1RAB9ASMN1; SMN2PPARGPPARA | |
| SCHEMBL6952971 | 0.91 | SMN1; SMN2 (0.65) | NPC1RAB9ASMN1; SMN2PPARGPPARA | |
| SCHEMBL6956586 | 0.87 | ALDH1A1 (0.50) | NPC1RAB9ASMN1; SMN2PPARGPPARA | |
| SCHEMBL6955359 | 0.84 | SMN1; SMN2 (0.63) | NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL6945113 | 0.84 | SMN1; SMN2 (0.63) | NPC1RAB9ASMN1; SMN2PPARGPOLB | |
| SCHEMBL6555749 | 0.84 | PPARG (0.64) | NPC1RAB9ASMN1; SMN2PPARGPPARA | |
| SCHEMBL8127443 | 0.84 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL6555630 | 0.83 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL6947575 | 0.83 | PPARG (0.63) | NPC1RAB9APPARGPPARAPPARD | |
| SCHEMBL6555767 | 0.82 | PPARG (0.68) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |