Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.52 |
| ▸ | PPARA | Q07869 | 5/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947290 | 0.91 | NPC1 (0.67) | SMN1; SMN2NPC1RAB9APOLBPPARG | |
| SCHEMBL6952459 | 0.90 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9APOLBGPR139 | |
| SCHEMBL6955348 | 0.84 | MAPK1 (0.63) | SMN1; SMN2NPC1RAB9APOLBPPARG | |
| SCHEMBL6950790 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9APOLBGPR139 | |
| SCHEMBL6945113 | 0.81 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9APOLBGPR139 | |
| SCHEMBL6949134 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9APOLBGPR139 | |
| SCHEMBL6955359 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9APOLBGPR139 | |
| SCHEMBL6947088 | 0.79 | PPARA (0.54) | NPC1PPARGPPARAPPARDHPGD | |
| SCHEMBL6951977 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9APOLBGPR139 | |
| SCHEMBL6951980 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9APOLBGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |