Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755810 | 0.82 | KMT2A (0.45) | TSHRCYP1A2CA1CA2KMT2A | |
| SCHEMBL9709460 | 0.77 | CYP1A2 (0.43) | TSHRCYP1A2KMT2APOLB | |
| SCHEMBL9698745 | 0.77 | KMT2A (0.43) | TSHRCYP1A2HTR2AKMT2APOLB | |
| SCHEMBL10435405 | 0.77 | POLB (0.39) | TSHRCYP1A2KMT2APOLB | |
| SCHEMBL28061290 | 0.77 | CYP1A2 (0.42) | TSHRCYP1A2KMT2APOLBMAPT | |
| SCHEMBL15463430 | 0.75 | CYP1A2 (0.38) | TSHRCYP1A2POLB | |
| SCHEMBL653721 | 0.75 | POLB (0.38) | TSHRCYP1A2KMT2APOLB | |
| SCHEMBL4906912 | 0.75 | CYP1A2 (0.41) | TSHRCYP1A2KMT2APOLBMAPT | |
| SCHEMBL3938274 | 0.74 | HTR2A (0.40) | TSHRCYP1A2HTR2ACA1CA2 | |
| SCHEMBL28152768 | 0.74 | KMT2A (0.39) | KMT2AFABP7FABP5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885189-B9 | METHOD FOR THE SYNTHESIS OF POLY-PYRROLE AND POLY-IMIDAZOLE CARBOXAMIDES ON A SOLID SUPPORT | CALIFORNIA INST OF TECHN (US) | 2003-04-02 | — | — | EP | claimed |
| EP-0885189-B1 | METHOD FOR THE SYNTHESIS OF POLY-PYRROLE AND POLY-IMIDAZOLE CARBOXAMIDES ON A SOLID SUPPORT | CALIFORNIA INST OF TECHN (US) | 2002-08-28 | — | — | EP | claimed |