Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 9/20 | 0.32 |
| ▸ | CTSS | P25774 | 6/20 | 0.32 |
| ▸ | CTSL | P07711 | 5/20 | 0.32 |
| ▸ | CTSB | P07858 | 3/20 | 0.32 |
| ▸ | CTSV | O60911 | 2/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942312 | 0.83 | ADAM17 (0.46) | ADAM17FCER2ALDH1A1 | |
| SCHEMBL6940320 | 0.82 | ADAM17 (0.58) | ADAM17RAB9ATAS1R3TAS1R1CTSK | |
| SCHEMBL6944677 | 0.82 | ADAM17 (0.40) | ADAM17 | |
| SCHEMBL6945567 | 0.81 | ADAM17 (0.44) | ADAM17KDM4E | |
| SCHEMBL6944319 | 0.81 | ADAM17 (0.45) | ADAM17 | |
| SCHEMBL6943561 | 0.81 | ADAM17 (0.67) | ADAM17ALDH1A1 | |
| SCHEMBL6945143 | 0.81 | ADAM17 (0.44) | ADAM17 | |
| SCHEMBL6944373 | 0.79 | ADAM17 (0.52) | ADAM17 | |
| SCHEMBL6942960 | 0.79 | ADAM17 (0.43) | ADAM17CTSKCTSSCTSLCTSB | |
| SCHEMBL6945603 | 0.79 | ADAM17 (0.38) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |