Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.73 |
| ▸ | DRD3 | P35462 | 5/20 | 0.73 |
| ▸ | DRD2 | P14416 | 4/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879246 | 1.00 | OPRM1 (0.73) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL12796706 | 0.98 | OPRM1 (0.71) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL2059948 | 0.98 | OPRM1 (0.71) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| Bromide SCHEMBL11150689 | 0.93 | OPRM1 (0.70) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL610828 | 0.92 | OPRM1 (0.74) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL4448222 | 0.92 | OPRM1 (0.74) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL612825 | 0.92 | OPRM1 (0.74) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL12128305 | 0.92 | KCNH2 (0.75) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL3854492 | 0.92 | OPRM1 (0.74) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL12540441 | 0.92 | OPRM1 (0.74) | OPRM1DRD3DRD2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709376-B1 | Phenylpiperidino derivatives as neurokinin antagonists | ASTRAZENECA AB (SE) | 2003-07-23 | — | — | EP | disclosed |