Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 5/20 | 0.71 |
| ▸ | DRD3 known ✓ | P35462 | 5/20 | 0.71 |
| ▸ | DRD2 known ✓ | P14416 | 4/20 | 0.71 |
| ▸ | OPRD1 known ✓ | P41143 | 4/20 | 0.71 |
| ▸ | OPRK1 known ✓ | P41145 | 4/20 | 0.71 |
| ▸ | KCNH2 known ✓ | Q12809 | 3/20 | 0.61 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.60 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.60 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.60 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.60 |
| ▸ | DRD1 known ✓ | P21728 | 1/20 | 0.60 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.60 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.60 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.60 |
| ▸ | BCHE known ✓ | P06276 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879246 | 0.98 | OPRM1 (0.73) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL6947636 | 0.98 | OPRM1 (0.73) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL12796706 | 0.96 | OPRM1 (0.71) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL23235958 | 0.92 | OPRM1 (0.72) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL5370094 | 0.92 | OPRM1 (0.72) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL5603796 | 0.92 | OPRM1 (0.72) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL10579648 | 0.92 | OPRM1 (0.72) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| Bromide SCHEMBL11150689 | 0.91 | OPRM1 (0.70) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL12128305 | 0.90 | KCNH2 (0.75) | OPRM1DRD3DRD2OPRD1OPRK1 | |
| SCHEMBL612825 | 0.90 | OPRM1 (0.74) | OPRM1DRD3DRD2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034289-A1 | POLYMERIZABLE COMPOSITIONS INCLUDING A POLYMERIZABLE COMPONENT AND A REDOX INITIATION SYSTEM CONTAINING A PHOTOLABILE REDUCING AGENT, AND A PHOTOLABILE REDUCING AGENT | 3M INNOVATIVE PROPERTIES COMPANY | 2025-01-30 | — | — | US | disclosed |
| US-20240400865-A1 | PHOTOPOLYMERIZABLE COMPOSITION, METHODS OF BONDING AND SEALING, AND AT LEAST PARTIALLY POLYMERIZED COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2024-12-05 | — | — | US | disclosed |
| EP-4423191-A1 | PHOTOPOLYMERIZABLE COMPOSITION, METHODS OF BONDING AND SEALING, AND AT LEAST PARTIALLY POLYMERIZED COMPOSITION | 3M Innovative Properties Company (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023166342-A1 | POLYMERIZABLE COMPOSITIONS INCLUDING A POLYMERIZABLE COMPONENT AND A REDOX INITIATION SYSTEM CONTAINING A PHOTOLABILE REDUCING AGENT, AND A PHOTOLABILE REDUCING AGENT | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023073444-A1 | PHOTOPOLYMERIZABLE COMPOSITION, METHODS OF BONDING AND SEALING, AND AT LEAST PARTIALLY POLYMERIZED COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-05-04 | — | — | WO | disclosed |
| US-11534264-B2 | Preformed dental composite crown, process of production and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-12-27 | — | — | US | disclosed |
| EP-3019141-B1 | HARDENABLE DENTAL COMPOSITION CONTAINING A MIXTURE OF AGGLOMERATED AND AGGREGATED NANOPARTICLES, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2022-08-31 | — | — | EP | disclosed |
| US-20200205935-A1 | PREFORMED DENTAL COMPOSITE CROWN, PROCESS OF PRODUCTION AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2020-07-02 | — | — | US | disclosed |
| EP-3426222-B1 | PREFORMED DENTAL COMPOSITE CROWN, PROCESS OF PRODUCTION AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2020-04-29 | — | — | EP | disclosed |
| EP-2670375-B1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2019-05-01 | — | — | EP | disclosed |
| EP-0270709-B1 | PROCESS FOR THE PRODUCTION OF VINYL POLYMERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4859750-A | Method for the production of polymethyl methacrylate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-08-22 | — | — | US | disclosed |
| US-4837286-A | EXCELLENT MOLD RELEASE WHEN POLYMERIZED AND MOLDED IN A MOLD | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0270709-A1 | Process for the production of vinyl polymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-15 | — | — | EP | disclosed |
| EP-0212980-A2 | Method for the production of polymethyl methacrylate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-03-04 | — | — | EP | disclosed |
| US-4544742-A | PROMOTERS FOR DENTAL PEROXIDIC POLYMERIZATIONS | SCHMITT WERNER (DE) | 1985-10-01 | — | — | US | disclosed |
| EP-0059451-B1 | 1,2,6-THIADIAZINE-3,5-DIONE-1,1 DIOXIDES AND THEIR USE | ESPE Fabrik Pharmazeutischer Präparate GmbH (DE) | 1985-07-31 | — | — | EP | disclosed |
| US-4443587-A | FOR ADDITION POLYMERS | ABITZ, MORF, GRITSCHNEDER (DE) | 1984-04-17 | — | — | US | disclosed |
| US-4125669-A | Bulletproof laminated safety glass and process for production | DEUTSCHE GOLD-UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4067853-A | ABRASION RESISTANT ACRYLIC POLYMERS FOR DENTURES | ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DT) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034289-A1 | POLYMERIZABLE COMPOSITIONS INCLUDING A POLYMERIZABLE COMPONENT AND A REDOX INITIATION SYSTEM CONTAINING A PHOTOLABILE REDUCING AGENT, AND A PHOTOLABILE REDUCING AGENT | PPOX, CYBA, SQOR | OPRM1 3215/4885DRD3 4220/4885DRD2 3871/4885 |
| US-11534264-B2 | Preformed dental composite crown, process of production and use thereof | CAD, ACR, USP7 | OPRM1 841/4885DRD3 3426/4885DRD2 2656/4885 |
| US-20200205935-A1 | PREFORMED DENTAL COMPOSITE CROWN, PROCESS OF PRODUCTION AND USE THEREOF | CAD, ACR, USP7 | OPRM1 841/4885DRD3 3426/4885DRD2 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.