Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517330 | 0.87 | LMNA (0.39) | THRBACHEALDH1A1LDHALDHB | |
| SCHEMBL508043 | 0.83 | THRB (0.56) | THRBACLYALDH1A1L3MBTL1LDHA | |
| SCHEMBL27598834 | 0.82 | THRB (0.52) | THRBACLYACHEALDH1A1L3MBTL1 | |
| Guanidine SCHEMBL508257 | 0.81 | THRB (0.43) | THRBACLYACHEALDH1A1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28539482 | 0.79 | THRB (0.53) | THRBACLYALDH1A1L3MBTL1LDHA | |
| Fluoride SCHEMBL10957150 | 0.79 | THRB (0.53) | THRBACLYALDH1A1L3MBTL1LDHA | |
| SCHEMBL28417052 | 0.79 | THRB (0.53) | THRBACLYALDH1A1L3MBTL1LDHA | |
| SCHEMBL4962834 | 0.79 | THRB (0.53) | THRBACLYALDH1A1L3MBTL1LDHA | |
| SCHEMBL5014759 | 0.79 | THRB (0.53) | THRBACLYALDH1A1L3MBTL1LDHA | |
| SCHEMBL28438581 | 0.79 | THRB (0.53) | THRBACLYALDH1A1L3MBTL1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333096-A1 | METHOD TO IDENTIFY GENE FUNCTION USING PHAGE DISPLAY SCREENING | Yale University (US) | 2003-08-06 | — | — | EP | disclosed |
| EP-1212453-A4 | METHOD TO IDENTIFY GENE FUNCTION USING SMALL MOLECULE PROBES | UNIV YALE (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-1212453-A1 | METHOD TO IDENTIFY GENE FUNCTION USING SMALL MOLECULE PROBES | Yale University (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001018234-A1 | METHOD TO IDENTIFY GENE FUNCTION USING SMALL MOLECULE PROBES | YALE UNIVERSITY (US) | 2001-03-15 | — | — | WO | disclosed |