Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | GCK | P35557 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947866 | 1.00 | MEN1 (0.65) | MEN1KMT2ANR4A2MAOBPTPN1 | |
| SCHEMBL6947103 | 0.93 | MEN1 (0.57) | MEN1KMT2ANR4A2MAOBPTPN1 | |
| SCHEMBL6947101 | 0.93 | MEN1 (0.57) | MEN1KMT2ANR4A2MAOBPTPN1 | |
| SCHEMBL6947812 | 0.93 | MEN1 (0.56) | MEN1KMT2ANR4A2MAOBPTPN1 | |
| SCHEMBL6947809 | 0.93 | MEN1 (0.56) | MEN1KMT2ANR4A2MAOBPTPN1 | |
| SCHEMBL14259572 | 0.90 | MAOB (0.55) | MEN1KMT2ANR4A2MAOBPTPN1 | |
| SCHEMBL6950492 | 0.89 | NR4A2 (0.67) | MEN1KMT2ANR4A2MAOBPTPN1 | |
| SCHEMBL6950489 | 0.89 | NR4A2 (0.67) | MEN1KMT2ANR4A2MAOBPTPN1 | |
| SCHEMBL6951893 | 0.88 | MEN1 (0.51) | MEN1KMT2ANR4A2MAOBPARP10 | |
| SCHEMBL6951889 | 0.88 | MEN1 (0.51) | MEN1KMT2ANR4A2MAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082121-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2003-02-05 | — | — | EP | claimed |
| EP-1082121-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2001-03-14 | — | — | EP | claimed |
| WO-1999062520-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 1999-12-09 | — | — | WO | claimed |
| US-20140243348-A1 | COMPOSITIONS AND METHODS FOR TREATING HERPES VIRUSES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243348-A1 | COMPOSITIONS AND METHODS FOR TREATING HERPES VIRUSES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-08-28 | — | — | US | disclosed |
| WO-2013028297-A1 | COMPOSITIONS AND METHODS FOR TREATING HERPES VIRUSES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-02-28 | — | — | WO | disclosed |
| EP-1082121-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2003-02-05 | — | — | EP | disclosed |
| US-6380249-B1 | HIV integrase inhibitors | MERCK & CO., INC. | 2002-04-30 | — | — | US | disclosed |
| EP-1082121-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999062520-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 1999-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243348-A1 | COMPOSITIONS AND METHODS FOR TREATING HERPES VIRUSES | EBNA1BP2, RPL17, TK2 | MEN1 3568/4885KMT2A 1917/4885NR4A2 2522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.