Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043633 | 0.90 | RAB9A (0.48) | TP53NPC1HPGDRAB9ACHEK1 | |
| SCHEMBL6043781 | 0.89 | CHKA (0.48) | TP53NPC1HPGDRAB9ACHEK1 | |
| SCHEMBL6043599 | 0.80 | MEN1 (0.50) | HRH3MEN1KMT2A | |
| SCHEMBL6043529 | 0.79 | KMT2A (0.49) | CHEK1HRH3MEN1KMT2AKDM4E | |
| SCHEMBL6043491 | 0.79 | MEN1 (0.52) | HRH3MEN1KMT2A | |
| SCHEMBL6044203 | 0.79 | HRH3 (0.49) | TP53HRH3MAOBMEN1KMT2A | |
| SCHEMBL6043654 | 0.78 | KMT2A (0.51) | CHEK1HRH3MEN1KMT2AKDM4E | |
| SCHEMBL6043682 | 0.78 | HRH3 (0.48) | TP53HRH3MAOBMEN1KMT2A | |
| SCHEMBL6042858 | 0.77 | TSHR (0.53) | TP53NPC1HPGDRAB9ACHEK1 | |
| SCHEMBL8284765 | 0.76 | LMNA (0.43) | HDAC6MEN1KMT2APARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |