Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | GAA | P10253 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | GLA | P06280 | 6/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29682930 | 0.87 | CYP3A4 (0.56) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL8373456 | 0.87 | CYP3A4 (0.56) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL16529438 | 0.87 | ALDH1A1 (0.55) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL18830028 | 0.87 | ALDH1A1 (0.51) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL9727774 | 0.87 | ALDH1A1 (0.71) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL7441541 | 0.85 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL5409626 | 0.85 | ALDH1A1 (0.54) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL29264039 | 0.85 | ALDH1A1 (0.54) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL28825145 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL3585477 | 0.84 | ALDH1A1 (0.52) | ALDH1A1GAAKDM4EHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |