Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.71 |
| ▸ | GAA | P10253 | 11/20 | 0.71 |
| ▸ | HPGD | P15428 | 9/20 | 0.71 |
| ▸ | GLA | P06280 | 8/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025131 | 0.87 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL16529438 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL6948296 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL29264039 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL5409626 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL28825145 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL3585477 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL30361197 | 0.83 | CA1 (0.52) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL26466636 | 0.83 | CA1 (0.52) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL11682561 | 0.81 | AKR1C4 (0.55) | ALDH1A1KDM4EGAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2754651-B1 | NITROBENZENE COMPOUND MANUFACTURING METHOD | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-9006477-B2 | Method for producing nitrobenzene compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-04-14 | — | — | US | disclosed |
| US-20140163256-A1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-06-12 | — | — | US | disclosed |
| US-5132314-A | For administration to mammals, anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| US-5081125-A | Substituted anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0420804-A2 | Anthelmintic compounds | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |
| EP-0101330-B1 | 2-QUINOLONE DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4526894-A | Antiinflammatory agents | NIPPON SHINYAKU CO. LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| US-4522945-A | SEROTONINE ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-06-11 | — | — | US | disclosed |
| EP-0101330-A2 | 2-Quinolone derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1984-02-22 | — | — | EP | disclosed |
| EP-0013612-B1 | (PIPERIDINYLALKYL)QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-11-09 | — | — | EP | disclosed |
| US-4335127-A | POTENT SEROTONIN ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-06-15 | — | — | US | disclosed |
| EP-0013612-A2 | (Piperidinylalkyl)quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163256-A1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | NOX1, NOS2, CYB5R3 | ALDH1A1 548/4885KDM4E 3790/4885GAA 2092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.