Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.38 |
| ▸ | PPARA | Q07869 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955086 | 0.84 | PPARG (0.36) | PPARGPPARAMAPTPTGESALOX5 | |
| SCHEMBL6952231 | 0.84 | PPARG (0.41) | PPARGPPARAMAPTPTGESALOX5 | |
| SCHEMBL6948413 | 0.82 | PPARG (0.36) | PPARGPPARAMAPTPTGESALOX5 | |
| SCHEMBL6956830 | 0.82 | PPARG (0.34) | PPARGPPARAMAPTPPARDALDH1A1 | |
| SCHEMBL6952576 | 0.80 | PPARG (0.45) | PPARGPPARAPPARD | |
| SCHEMBL6953968 | 0.76 | PPARG (0.35) | PPARGPPARAMAPTPPARDTP53 | |
| SCHEMBL6948887 | 0.74 | PPARG (0.41) | PPARGPPARAMAPT | |
| SCHEMBL8796655 | 0.74 | FFAR1 (0.55) | PPARGPPARAMAPTFFAR1TP53 | |
| SCHEMBL8301557 | 0.73 | NPC1 (0.43) | PPARGPPARAPPARDALDH1A1MEN1 | |
| SCHEMBL6948555 | 0.72 | PPARG (0.43) | PPARGPPARAPPARDRAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |