Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948411 | 0.84 | PPARG (0.38) | PPARGPPARAMAPTFFAR1ABCB1 | |
| SCHEMBL6952231 | 0.84 | PPARG (0.41) | PPARGPPARAMAPTPTGESALOX5 | |
| SCHEMBL6948413 | 0.82 | PPARG (0.36) | PPARGPPARAMAPTFFAR1ABCB1 | |
| SCHEMBL6948917 | 0.80 | PPARG (0.40) | PPARGPPARAITGB3ITGA2B | |
| SCHEMBL6954155 | 0.80 | PPARG (0.43) | PPARGPPARAITGB1ITGB3ITGA2B | |
| SCHEMBL6954989 | 0.74 | PPARG (0.41) | PPARGPPARAMAPTHRH1HRH3 | |
| SCHEMBL8796655 | 0.74 | FFAR1 (0.55) | PPARGPPARAMAPTFFAR1HRH3 | |
| SCHEMBL8302608 | 0.73 | NPC1 (0.43) | PPARGPPARAHRH1HRH3ITGB3 | |
| SCHEMBL6948555 | 0.72 | PPARG (0.43) | PPARGPPARA | |
| SCHEMBL8796663 | 0.71 | FFAR1 (0.36) | PPARGMAPTFFAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |