Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.34 |
| ▸ | PPARA | Q07869 | 10/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956839 | 0.83 | PPARA (0.34) | PPARGPPARAKDM4EALDH1A1MAPT | |
| SCHEMBL6948411 | 0.82 | PPARG (0.38) | PPARGPPARAKDM4EALDH1A1MAPT | |
| SCHEMBL6952576 | 0.81 | PPARG (0.45) | PPARGPPARAPPARD | |
| SCHEMBL6956469 | 0.76 | PPARA (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6948887 | 0.76 | PPARG (0.41) | PPARGPPARAMAPT | |
| SCHEMBL6953968 | 0.75 | PPARG (0.35) | PPARGPPARAMAPTNPSR1PPARD | |
| SCHEMBL6953527 | 0.74 | THRB (0.37) | PPARGPPARAALDH1A1MAPTHRH1 | |
| SCHEMBL6948555 | 0.73 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6947127 | 0.73 | ALDH1A1 (0.40) | PPARGPPARAALDH1A1MAPTNPSR1 | |
| SCHEMBL8797128 | 0.73 | HRH3 (0.50) | PPARGPPARAALDH1A1MAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |